The fluoride issue, a perennial hot potato, is heating up once again. In Britain, the government has recently announced its intention to fluoridate the water of deprived inner city areas, supposedly to improve the dental health of children living there. Later, water fluoridation may be introduced nationwide. A White Paper outlining the government's plans is scheduled for this spring.

The government and the dental profession have convinced the public that fluoridated water offers nothing but benefits that there is overwhelming evidence that it prevents tooth decay and contributes to the strength of bones. There is tacit admission in the pro fluoride camp that fluoride can also cause harm, but only at high levels: more than 2 ppm in water may cause mottled teeth and over 8 ppm may lead to bone disorders and degenerative changes in the vital organs.

A few lone voices have countered the prevailing view, with published evidence that fluoride can have devastating effects, causing mottled teeth and osteoporosis at very low levels. While much has been written about the effects of too much fluoride on teeth and bones, little is known about the effects of fluoride on the rest of the body.

But new evidence has emerged demonstrating that it can have devastating effects on just about every organ in the body, and may even be partly responsible for behavioural problems like hyperactivity and many puzzling illnesses like ME.

Like mercury, fluoride isn't exactly an obvious choice for dental health as it is a poison more poisonous than lead and only slightly less poisonous than arsenic (Clin Toxicol Commerc Prod, 1984; 11: 4, 112, 129, 138). It's been used as a pesticide, and it's a component in fungicides, rodenticides, anaesthetics and many drugs. The fluoride used in toothpaste, mouth rinses and dental gels is usually sodium fluoride, a waste product from the aluminium industry. Fluoride added to our water supply is hydrofluorosilic acid or sometimes silicofluoride waste products of fertiliser and glass industries.

The late US fluoride critic George L Waldbott discovered that, besides teeth and bones, fluoride can damage soft tissue. According to his research, the small fluorine ion with a high charge density can penetrate every cell of the body and combine with other ions (GL Waldbott et al, Fluoride: The Great Dilemma, Lawrence, Kansas: Corenado Press, 1978: 148-74). It interferes with the metabolism of calcium and phosphorus and the function of the parathyroid glands.

It has a strong affinity to calcium, but will also readily combine with magnesium and manganese ions and so can interfere with many enzyme systems that require these minerals. The interruption of these enzyme systems, in turn, may disturb carbohydrate metabolism, bone formation and muscle function. Indeed, every vital function in the body depends on enzymes; because fluoride easily reaches every organ, many diverse toxic symptoms can result.

Fluoride and enzymes

Enzyme systems react to fluoride in different ways; some are activated, others are inhibited. Lipase (essential for the digestion of fat) and phosphatases (needed to breakdown phosphates) are very sensitive to fluoride. In patients with skeletal fluorosis, succinate dehydrogenase activity is inhibited. In chronic fluoride poisoning, this diminished enzyme activity accounts for muscular weakness and even muscle wasting. Human salivary acid phosphatase is diminished by half when exposed to 3.8 ppm of fluoride. The blood enzyme cholinesterase is inhibited by 61 per cent on exposure to 0.95 ppm fluoride an amount within recommended levels adversely affecting functions of the nervous system (PA Smith, ed, Handbook of Experimental Pharmacology, Berlin: Springer Verlag, 1970: 48-97).